Gaa na Ọdịnaya
 
International Parkinson and Movement Disorder Society

Nsonaazụ nnwale ụlọ ọgwụ kacha ọhụrụ na-akwado ịdị adị ogologo oge nke ọgwụgwọ ọgwụ abụọ na-eji nwayọ nwayọ nke Friedreich's ataxia.

October 5, 2025

HONOLULU, HAWAII, USA - Ọgwụgwọ na-agbanwe ọrịa maka nsogbu mmegharị ahụ dị ụkọ, mana nsonaazụ sitere na nnwale ụlọ ọgwụ abụọ na-egosi ụzọ abụọ dị mma maka ndị nwere Friedreich's ataxia (FA), dịka data ewepụtara na International Congress of Parkinson's Disease and Movement Disorders® na Honolulu. 

"Nchọpụta ndị dị na nchịkọta akụkọ ndị a na-akpali akpali maka ikike ha nwere ịgbanwe echiche dị ogologo oge maka ndị nwere Friedreich's ataxia," Dr. Liana Rosenthal, Prọfesọ Prọfesọ nke Neurology na Ụlọ Akwụkwọ Ọgwụ nke Mahadum Johns Hopkins kwuru. "Ha na-egosi na ọtụtụ ndị ọrụ na-egosipụta ugbu a uru na-adịgide adịgide na FA. N'ụzọ sara mbara, ha na-egosipụta mgbanwe na Mgbanwe Mgbanwe na usoro ọgwụgwọ na-agbanwe ọrịa, na-enye ihe atụ maka ogologo oge nleba anya na data akụkọ ihe mere eme nke okike nwere ike iduzi ọganihu na ọrịa ndị ọzọ na-adịghị ahụkebe na-adịghị ahụkebe. " 

Vatiquinone bụ onye na-emechi ọnụ nke mbụ na klas nke 15-lipoxygenase n'okpuru nyocha maka ọgwụgwọ FA, ọrịa nke na-enwe ọganihu na-adịghị mma nke na-emetụta gait na nguzozi, na-emecha na-eduga ná nkwụsị nke ambulation. N'ime nyocha ogologo oge, ndị na-eme nchọpụta tụlere nsonaazụ ọnwa 24 site na nyocha nke 2 nke vatiquinone na-achịkwa placebo na ndị otu akụkọ ihe mere eme nke dabara adaba iji nyochaa mmetụta ọgwụgwọ vatiquinone na-aga n'ihu ọrịa na ambulatory na ndị okenye na-abụghị ndị nwere FA.    

Ndị ọrịa na-anata vatiquinone gosipụtara mmụba nke 0.917 na akara mFARS, ebe ndị otu akụkọ ihe mere eme sitere n'okike gosipụtara ihe 3.892 na-akawanye njọ, -4.809 opekata mpe square pụtara ọdịiche na-akwado vatiquinone (P <0.0001). A nabatara ọgwụ ahụ nke ọma n'enweghị ihe omume ọjọọ metụtara ọgwụgwọ, na-akwadokwa na iji vatiquinone ogologo oge na-echekwa ọrụ nke ọma.   

N'otu aka ahụ, ndọtị akara ngosi nke nnwale ụlọ ọgwụ dị iche nyochara ogologo oge iji omaveloxolone, ọgwụ ọnụ akwadoro maka ọgwụgwọ FA. N'ime ọmụmụ ihe kachasị ogologo nke usoro ọgwụgwọ ọrịa na-eme mgbanwe na ndị ọrịa nwere FA, ndị na-anata omaveloxolone n'ime afọ 4 gosipụtara ọganihu ọrịa nwayọọ nwayọọ ma e jiri ya tụnyere ndị otu akụkọ ihe mere eme nke okike, na-enweghị nnukwu njọ nke ọrụ bulbar na nhazi nke elu.  

"N'ihi na nkwụsị na-aga n'ihu bụ ogologo oge a na-atụ anya na FA, nchọpụta ndị a na-ebuli ezi olileanya na usoro ọgwụgwọ ezubere iche nwere ike gbanwee usoro ọrịa ahụ," ka Dr. Rosenthal kwuru. "Ha na-egosikwa otú ndị otu akụkọ ihe mere eme sitere n'okike siri dị na ọnọdụ ndị na-adịghị ahụkebe yana ihe anyị na-amụta site na nleba anya ogologo oge gbasara ma mmetụta nchekwa na ọgwụgwọ. 

"N'ịkọkọta ọnụ, nchọpụta ndị a na-egosi ezigbo ọganihu." 

Ederede n'uju nke abstract dị na mdsabtracts.org. 

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Amegide 2025 MDS International Congress of Parkinson's Disease and Movement Disorders®:  

MDS International Congress bụ mmemme kwa afọ nke izizi iji kwalite ọzụzụ ahụike na sayensị nke ọrịa ngagharị, gụnyere ọrịa Parkinson. Na-akpọkọta puku kwuru puku ndị isi ụlọọgwụ, ndị ọkà mmụta sayensị na ndị ọkachamara ahụike ndị ọzọ si gburugburu ụwa, International Congress ga-ewebata ihe karịrị 1,800 abstracts sayensị wee nye ọgbakọ maka agụmakwụkwọ na imekọ ihe ọnụ na nyocha na ọgwụgwọ ọhụụ. 

Banyere International Parkinson and Movement Disorder Society: 
International Parkinson and Movement Disorder Society® (MDS), otu mba ụwa nke ihe karịrị ndị ụlọ ọgwụ 12,000, ndị ọkà mmụta sayensị, na ndị ọkachamara ahụike ndị ọzọ, raara onwe ha nye iji kwalite nlekọta ndị ọrịa site na agụmakwụkwọ na nyocha. Maka ozi ndị ọzọ gbasara MDS, gaa na www.movementdisorders.org.