Nsonaazụ sitere na nnwale ụlọ ọgwụ na agba nke Atọ maka infusion subcutaneous nke Foslevodopa/Foscarbidopa
Kpọtụrụ ndị mmekọ: Shea Higgins +1 304-633-3396, shiggins@movementdisorders.org
MILWAUKEE, WI, USA – Na-aga n'ihu subcutaneous infusion (CSCI) nke levodopa / carbidopa prodrugs, foslevodopa / foscarbidopa, mma oge na-enweghị dyskinesia na ndị ọrịa nwere elu Parkinson ọrịa (PD) dị ka a na-adọ 3 clinical ikpe wepụtara taa na International Congress of Parkinson's Disease and Movement Disorders® na Madrid, Spain.
A maara nke ọma na ogologo oge iji ọnụ levodopa/carbidopa na-eduga na ụba dyskinesia na ndị ọrịa PD. A na-eche na mgbaàmà moto ndị a bụ n'ihi ịrị elu na ọdịda nke dopamine. Ya mere, ọtụtụ nyocha emeela iji nyere aka na-agwọ ma gbochie mmepe nke levodopa-induced dyskinesia.
Ọnwụnwa ụlọọgwụ nke 3 nke Soileau et al mere. nyochara arụmọrụ na nchekwa nke 24-hour CSCI foslevodopa / foscarbidopa, na ndị ọrịa nwere PD dị elu. Otu narị ndị ọrịa iri anọ na otu bụ 1: 1 iji nweta CSCI nke foslevodopa/foscarbidopa na placebo ọnụ ma ọ bụ CSCI nke placebo na ọnụọgụ levodopa / carbidopa maka izu iri na abụọ. Ọgwụgwọ na CSCI nke foslevodopa/foscarbidopa mere ka ọ dịkwuo mma n'oge na-enweghị dyskinesia mgbe a tụrụ ya na izu 12.
Werner Poewe, Prọfesọ nke Neurology na Medical University Innsbruck, Austria, zara nke a ọmụmụ, "Nke a na-amụ bụ ihe dị mkpa dị ịrịba ama na mmepe nke na-aga n'ihu ọgwụ-enyefe azum na-emeso moto fluctuations na PD egosi ịrịba mmụba na ON-oge na-enweghị nsogbu dyskinesias iji subcutaneous 24-hour infusions nke a akwụkwọ akụkọ levodopa ụdị gara aga size / carbi. levodopa / carbidopa intestinal gel infusions na nsonaazụ nke abụọ na-egosi uru na ụra na ọrụ moto nke ụtụtụ na-egosi na ọ dabara na ihe a maara site na infusions apomorphine na-aga n'ihu na PD, na-atụ aro na n'oge na-adịghị anya a ga-agbakwunye infusions nke levodopa na Pọtụfoliyo nke nhọrọ ọgwụgwọ na ndị ọrịa PD nwere nsogbu levodopa.
Ederede abstract zuru ezu: mdsabtracts.org. Ntụaka #: 775
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